The risk is increased with higher dosages, a shorter interval between doses, in people who drink three or more alcoholic drinks per day, when taken with other medications that also contain acetaminophen, and in patients with pre-existing liver disease.
Tylenol is an effective mild pain reliever with a low risk of side effects but the potential for liver damage exists, even at recommended dosages. Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. May interact with some other medications including warfarin. May not be suitable for some people including people who regularly consume three or more glasses of alcohol per day and those with liver disease. Considered less effective for pain relief than NSAIDs but associated with a lower risk of side effects. Acetaminophen is often included in cold and flu remedies, and it may be easy to inadvertently double up on an acetaminophen dose. An overdose of acetaminophen can damage your liver and cause death. The potential for liver damage exists, even at recommended dosages. May cause gastrointestinal side effects at high dosages. Rarely, may cause itchiness, constipation, nausea, vomiting, headache, insomnia, and agitation. If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Tylenol is available as a generic under the name acetaminophen. Available in a range of formulations including liquid, oral tablets, oral disintegrating tablets, chewable tablets, controlled-release tablets, dispersible tablets, injectable, and rectal preparations. May be combined with strong opioids for the treatment of severe pain. When used at low dosages, it lacks gastrointestinal side effects associated with NSAID pain relievers (does not cause ulcerations, bleeding, or perforations). 
First choice for mild-to-moderate pain due to its efficacy, minimal toxicity, and low cost.Also, lowers a fever but does not control inflammation.May be used in the treatment of many conditions such as arthritis, backache, colds, menstruation pain, muscle aches, and toothache. Effective for the temporary relief of minor aches, pains, and headaches.It may also be called an antipyretic because it will bring down a fever. Tylenol belongs to the class of medicines called analgesics (pain relievers) it is specifically a non-narcotic analgesic.
Experts aren't sure exactly how acetaminophen works, but suspect it blocks a specific type of cyclo-oxygenase (COX) enzyme, located mainly in the brain. Tylenol is a brand (trade) name for acetaminophen and is used to relieve pain.Medically reviewed by Carmen Pope, BPharm.
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